Hormesis and Trade-Offs: A Comment

Hormesis and trade-offs: a comment.

Single or multiple exposures to mild stress at younger ages often have positive health beneficial effects throughout life, indicating that rescue systems turned on at a young age can be effective even in old age (e.g. Le Bourg 2011). This seems to be at variance with the notion of the so-called trade-offs that due to a limitation of resources it is impossible for an organism to increase all asp...

Hormesis Results in Trade-offs with Immunity

Many have argued that we may be able to extend life and improve human health through hormesis, the beneficial effects of low-level toxins and other stressors. But, studies of hormesis in model systems have not yet established whether stress-induced benefits are cost free, artifacts of inbreeding, or come with deleterious side effects. Here, we provide evidence that hormesis results in trade-off...

Defining Pathways and Trade-offs Toward Universal Health Coverage; Comment on “Ethical Perspective: Five Unacceptable Trade-offs on the Path to Universal Health Coverage”

The World Health Organization’s (WHO’s) World Health Report 2010, “Health systems financing, the path to universal coverage,” promoted universal health coverage (UHC) as an aspirational objective for country health systems. Yet, in addition to the dimensions of services and coverage, distribution of coverage in the population, and financial risk protection highlighted by the report, the conside...

Trade-offs

23. Stent, G.S. (1972). Prematurity and uniqueness in scientific discovery. Sci. Am. 227, 84–93. 24. Mirsky, A.E., and Pollister, A.W. (1946). Chromosin, a desoyribose nucleoprotein complex of the cell nucleus. J. Gen. Physiol. 30, 117–148. 25. Boivin, A. (1947). Directed mutation in colon bacilli, by an inducing principle of desoxyribonucleic nature: Its meaning for the general biochemistry of...

A one-model approach for Computation of congestion With productions trade-offs and weight restrictions